Vice President, Clinical Science & Development

Aarhus/Copenhagen, Denmark, with flexibility for broader Europe or the United States.

About NMD Pharma

NMD Pharma is a clinical-stage biotech company dedicated to developing novel and improved treatments for people living with neuromuscular diseases. The company is advancing a first-in-class platform of small molecule therapies targeting the skeletal muscle chloride ion channel ClC-1 to improve muscle function and quality of life for patients with significant unmet medical needs.

Headquartered in Aarhus, Denmark, NMD Pharma combines deep scientific expertise in muscle physiology and neuromuscular disorders with a collaborative and entrepreneurial culture focused on advancing innovative therapies through clinical development.

The Position

Reporting to the Chief Medical Officer, the Vice President, Clinical Science & Development will lead the clinical development strategy and pivotal clinical programme execution for NMD Pharma’s lead neuromuscular asset.

This is a key leadership role requiring both strategic thinking and hands-on execution in a lean biotech environment. You will work closely with Clinical Operations, Regulatory Affairs, Data Sciences, Safety, CMC, and external partners to ensure the programme is scientifically credible, operationally feasible, statistically robust, and regulator-ready.

• Lead the global clinical development strategy for pivotal neuromuscular programmes from late-stage clinical phase through registration.
• Provide clinical-scientific leadership across the programme, ensuring that development strategy is grounded in disease biology, patient relevance, and robust clinical evidence.
• Define study strategy including patient population, endpoints, estimands, comparators, powering assumptions, and clinical meaningfulness.
• Lead or oversee development of key clinical documents, including protocols, clinical study reports, investigator brochures, and clinical sections of regulatory submissions
• Lead cross-functional programme governance, risk management, and decision-making processes.
• Drive neuromuscular endpoint and biomarker strategy, integrating translational insights and functional, clinician-reported, patient-reported, and digital endpoints where relevant.
• Partner closely with Data Sciences to ensure a robust statistical strategy, including approaches to statistical methodology, missing data, multiplicity, covariates, and sensitivity analyses.
• Co-lead FDA and EMA interactions, including briefing books, scientific advice meetings, and registration strategy discussions.
• Provide medical and scientific leadership on safety monitoring, benefit-risk evaluation, eligibility criteria, and study oversight.
• Lead, develop, and grow the Clinical Development team, fostering a culture of scientific excellence, accountability, collaboration, and continuous development.
• Partner with Clinical Operations to build and oversee a scalable external vendor and CRO model to support efficient pivotal programme execution.
• Establish strong relationships with investigators, key opinion leaders, patient advocacy groups, and external scientific experts.

• MD; Clinical experience in Neurology is preferred. PhD or PharmD with significant clinical development leadership experience also considered.
• Strong understanding of neuromuscular disease development and endpoint strategy strongly preferred
• At least 10 years of significant biotech and/or pharmaceutical clinical development experience with increasing leadership responsibility.
• Proven experience leading pivotal or Phase 3 clinical programmes, including designing pivotal trials, creating clinical trial protocols, driving the interpretation of clinical study reports and other relevant clinical documents.
• Experience interacting with FDA and EMA in late-stage development programmes.
• Strong understanding of clinical trial design, biostatistics, safety, and regulatory requirements.
• Strong people leadership experience with a track record of creating team alignment, developing talent, and driving performance through periods of growth and change.

Personal Competencies

You are a collaborative and scientifically strong leader who combines strategic thinking with operational execution. You bring:

• Strong scientific and clinical judgement.
• Excellent communication and stakeholder management.
• The ability to build trust, engagement, and commitment through authentic leadership and communication.
• A pragmatic and solutions-oriented approach.
• Executive presence and confidence in external interactions.

Why Join NMD Pharma?

This is an opportunity to play a central role in shaping a late-stage neuromuscular development programme with significant potential patient impact.

At NMD Pharma, you will join a collaborative and science-driven organisation where you can influence strategy, work closely with senior leadership, and contribute directly to the company’s future growth.

Application

Please submit your application and CV as soon as possible. Applications are reviewed on an ongoing basis.

NMD Pharma is committed to creating an inclusive workplace and welcomes applications from all qualified candidates.

Apply with QuickApply on Jobindex.